Dendritic Cell Therapy in Germany – Personalized Immunotherapy
GermanyHealth connects you with licensed immunotherapy specialists and clinics in Germany.
Licensed Partner Clinics
GMP certified labs
Since 2010
Honest assessment
Treatment by Cancer Type
Dendritic Cell Therapy for Your Type of Cancer
Every cancer is different, and so is the way the immune system responds to it. That’s why the specialists plan dendritic cell therapy individually for each type of cancer: which tumor antigens are used, which therapies are combined with the vaccine, and how many treatment cycles make sense. Choose your cancer type to read how the treatment is used for it.
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Your cancer type isn’t listed? The specialists review every case individually. Request your free case review →
DENDRITIC CELL VACCINATION
What Is Dendritic Cell Therapy for Cancer?
Dendritic cell therapy is a personalized cancer immunotherapy. Dendritic cells are the immune system’s scouts: they show T cells what to attack.
For the therapy, they are produced from your own blood, loaded with antigens from your tumor in a laboratory, and given back to you as a vaccine. The aim is to train your immune system to recognize the cancer cells.
Before the vaccine is made, the treatment starts with NVD virotherapy. Newcastle disease virus, a bird virus that is harmless to humans, is used to trigger immunogenic cell death (ICD) in tumor cells.
As these cells die, they release their tumor antigens together with danger signals that alert the immune system. These antigens are what the dendritic cells are loaded with in the laboratory, so the vaccine is directed against the features of your own tumor.
- Made from your own cells
- Produced in a GMP laboratory
- Usually 2-4 vaccinations
FIVE STEPS TO YOUR PERSONAL VACCINE
STEP 1
NVD virotherapy
Newcastle disease virus triggers immunogenic cell death: tumor cells release their antigens and a danger signal.
STEP 2
Cell collection
Immune cells (monocytes) are collected from your blood.
STEP 3
Laboratory
In about 8 days they mature into dendritic cells in a GMP laboratory.
STEP 4
Antigen loading
The dendritic cells are loaded with the tumor antigens released in step 1.
STEP 5
Vaccination
The vaccine is injected into the skin and activates your T cells.
Is Dendritic Cell Therapy Right for You?
Dendritic cell therapy is a personalized immunotherapy made from your own immune cells. It is not suitable for every patient, and we believe you deserve an honest assessment before you consider treatment. Every case is reviewed individually by experienced immunotherapy specialists at licensed partner clinics in Germany. The points below give you a first orientation.
You May Be a Candidate If You...
- you don't want or can't undergo standard treatment such as surgery, chemotherapy or radiation
- have completed standard treatment such as surgery, chemotherapy or radiation, and want to explore a next step
- have experienced a recurrence or have advanced or metastatic cancer (including stage 4)
- are in a reasonably stable general condition, meaning you can largely take care of yourself and travel to Germany
Usually Not Suitable If You...
- have a rapidly progressing, very large tumor burden that first needs to be reduced by other treatments
- depend on high-dose corticosteroids or other immunosuppressive drugs
- have an active autoimmune disease or have received an organ transplant
- are in a very weak general condition
Not sure where you stand?
Many patients don’t fit neatly into one list, and that’s normal. Send us your medical reports for a free, non-binding case review. We forward them to the specialists at our partner clinics, who will assess honestly whether dendritic cell therapy is a reasonable option for you. If it isn’t, we’ll tell you that too.
immunotherapy
Immunotherapy programs in Germany
ICD Immunogenic cell death therapy gives the danger signal to detect the tumor antigens. This signal is essential for maturing the dendritic cells.
The Treatment Protocol
How the Combined Treatment Works - Step-by-Step
NDV virotherapy first, then 2–4 dendritic cell vaccinations.
NVD virotherapy
Sends a “danger signal” that makes the tumor visible
Personal vaccine
Cells loaded with tumor antigens in a GMP lab
2-4 vaccinations
Each dose reinforces the T-cell training
Monitoring
Blood values, immune markers, imaging
Your Journey starts here
What to Expect: Time, Travel and Stay in Germany
Week 0
Case review, Zoom call
10-14 days
Treatment start
1st Stay
12-14 days in Germany
2nd Stay
4 weeks later / 12-14 days
Honest Information
What the Research Shows – and What It Doesn't
NDV virotherapy first, then 2–4 dendritic cell vaccinations.
ICD virotherapy
Well tolerated; benefit for some patients
What is still uncertain
Results vary; no guarantees
Transparent Cost
What Does Dendritic Cell Therapy Cost?
Combined Immunotherapy Program
Starts at €57,000
What affects the price
Vaccine Complexity · cycles · add-on-therapies / ICD Immunogenic Cell Death Therapy, 2 – 4 Dendritic Cell Therapies, Checkpoint inhibitors, Hyperthermia sessions
“Not included”
Cost for flight ticket, accommodation and daily living expenses included.
Immunotherapy Specialists at Our Partner Clinics
Prof. Dr. med. van Gool
Van Gool, MD, PhD, is a specialist in pediatric and adult hematology-oncology with a focus on brain tumors but also center in general.
PhD rer. nat. Nesselhut
Dr. Nesselhut is specialist in Immunotherapies and board certified physician in immunotherapy. His focus is at oncological immunotherapy and DCV.
Dr. med. Stücker
Dr. Stücker is count among the renowned scientists and physicians in the fields of immuno-oncology and translational oncology.
Prof. Dr. Stehling
University Professor of Radiology, Jerusalem University (AQU),
fmr. Fellow Harvard Medical School and Associate Professor of Radiology, Boston
Patient Experience
What Our Patients Say
Medical Concierge Service
GermanyHealth: Making The Connection
WE COORDINATE, SO YOU CAN FOCUS ON TREATMENT.
We coordinate and organize your appointments
Medical Concierge Service
We organize your transportation and accommodation
Accompanying service in the clinic
FREE CASE REVIEW
What to Send for Your Case Review
- Confidential under GDPR
The information we need
- Pathology report
- Current blood tests
- Treatment history - Fill the questionnaire here
Questions Patients Ask About Dendritic Cell Therapy
Are there side effects, and how severe are they?
“Yes, like all medical treatments, dendritic cell vaccination and other immunotherapies can have side effects—but they are generally much milder compared to chemotherapy or radiation. Most patients experience only mild flu-like symptoms such as fatigue, fever, or soreness at the injection site.
However, these effects usually go away within a day or two. Serious side effects are rare, especially with dendritic cell therapy, because it works with your body’s natural immune system.
The doctor will closely monitor every patient and personalize the treatment to minimize risks as much as possible.”
Side effects exist but are typically mild.
Dendritic cell vaccination is known for being well-tolerated.
Monitoring and personalization reduce risks.
Compared to chemo or radiation, the body handles it much better.
What is the success rate of dendritic cell therapy?
“The success rate of DCT depends strongly on the type and stage of your cancer, as well as your overall health and how your immune system responds."
However, in some cancers like melanoma, non-small cell lung cancer, glioblastoma, pancreatic cancer, prostate cancer or certain lymphomas, immunotherapy has shown good results.
For other cancers, it may be used to slow progression, improve quality of life, or support other treatments.
That’s why we offer personalized evaluations to determine if this therapy is likely to be effective in your specific case. Hence the goal of GermanyHealth is always to find the best approach for your unique condition.”
How soon can I start, and how long does it take?
Normally within 10-14 days, once we got all your files!
Request Your Free Case Review
Your dates and a cost estimate, prepared by the specialists. Free, non-binding, confidential under the GDPR.
Mon–Sat, 9 am – 8 pm (Germany time)
